Thanks for any help you guys have for me.
**Edit: There are around 5 portals in every participating land but you can go the same portals multiple times and see different villains or parts of the same villain story. There is Cruella on Main Street; Ursula, Maleficent, and Chernabog in Fantasyland; Scar, Yzma, and Jafar in Adventureland; and Ratcliffe and Dr. Facilier in Liberty Square/Frontierland.
The game itself on easy only takes like 30 minutes to play one villain. At that point you are given the option to either stop there for the day and pick it up another time or continue to another land with another villain. If there are long lines for the portals one villain on easy could take over an hour but you don't have to continue immediately, you can stop and pick it back up whenever you want.
As a tip if you want more cards to play with (not trade) you can find them online and print them out on card stock. If you cut them out they work the same way for the game (as long as you have at least one real card with the back to show if needed) but you can't trade them.
Walt Disney World's Magic Kingdom
Disney's Animal Kingdom
Disney's Hollywood Studios
Disney California Adventure
Universal Studios Florida
Universal's Islands of Adventure
Universal Studios Hollywood